Wouldn’t it be helpful to know if a medication was going to work before you took it?

With Pharmacogenomics,
now you can!

Ever wonder why some medications work better — or worse — for you than for a family member or friend? The answer lies in Pharmacogenomics! 

Pharmacogenomics (PGx) is the study of a person’s genes to identify changes that will affect how their bodies process medications. A medication that helps one person may be harmful for another, just based on the smallest difference in their genes.

Why do People Respond Differently to Certain Medications? 

Our genes are made of DNA. Just as genes help determine our eye or hair color, they also play a role in how each person’s body responds to medications. Certain genes help break down and process drugs. A change (also called a “variant”) in one of these genes can make your body process a drug in different ways.

If a medicine is broken down too quickly, the amount in a person’s body may be too low for it to work well. If it breaks down too slowly, the amount of medicine in a person’s body could build up causing an uncomfortable side effect. On rare occasions, certain changes in these genes can cause a serious reaction. If your healthcare provider understands these changes, you can be given the right medication or right dose that will work the best for you with the fewest side effects.

By looking for changes in certain genes, your PGx test can predict how your body responds to or metabolizes specific drugs. 
Your body’s response may be described by one of the following:


No function

Your body may be 
unable to process 
the drug

Poor metabolizer

(poor function)

Your body may process the drug very slowly

Intermediate metabolizer

Your body may process the drug slowly

Normal function

Your body should process the drug normally

Rapid metabolizer (increased function)

Your body may process the drug quickly

Ultrarapid metabolizer

Your body may process the drug very quickly

Uncertain

Your body’s expected response to the drug is unclear

Does PGx Testing Benefit You?

Your personalized PGx results will help your doctors:

Improve drug efficacy

Your doctors can select drugs more
likely to work well for you. 

Reduce adverse

side effects

Your doctors can know in advance to avoid 
selecting a potentially harmful medication, 
or medications that shouldn’t be taken together, which reduces your chance for unwanted side effects.

Select the best dose


Your doctors can determine how much and how often you should take a medication to 
avoid ineffective underdosing or 
toxic overdosing.

What does this mean for you? 

Better symptom relief 
Peace of mind knowing you're taking the right medication for you
Fewer trips to the doctor 
for medication changes
Avoid taking a medication
that could harm you

We Make Your Data Privacy Our Top Priority

Genetic data is sensitive information. At InformedDNA, we understand this and

set your privacy and data protection as our number 1 priority.
  • We will NEVER disclose any genetic or personal data to employers, insurance companies, public databases, or third-party marketers without your explicit consent — you have complete control over how your information is used and who it is shared with.

  • We maintain a robust data security program, adhering to strict industry data protection standards. All sensitive information is encrypted, and regular assessments are conducted to detect and address security vulnerabilities and threats.

  • We do not divulge individual-level personal information to law enforcement unless compelled by a court order, subpoena, search warrant, or other legally valid requests. Your privacy is our commitment.

For more information on your rights and our responsibilities regarding your private health information, please read our Notice of Privacy.

Pharmacogenomics: Credibility by the Numbers

Use of genetic tests to guide drug choices is becoming more common and is growing 
in reliability and importance each day. Studies have shown:

0 %

of people have gene variants
that change how their body
reacts to medicine1

0 %
have said they would be comfortable getting a genetic test 
to find one of these variants2
0 %
35-65% of people have used at 
least one of the common medications that variants can impact3

Notable Milestones in Pharmacogenomics 
Discovery and Evolution

See how early knowledge of genes and medicine connected to become the study of Pharmacogenomics —
a safe tool for better medication management for you!

510 BC

Pythagoras noted that eating fava beans resulted in a potentially fatal reaction in some, but not all. This was later found to be due to a deficiency of a specific enzyme — G6PD.

1962

From the exploration of genetics and drug responses over time, scientists were able to publish the first textbook named “Pharmacogenetics: Heredity and the Response to Drugs.”

1980s - 1990s

The first genetic changes impacting drug processing were discovered in two genes — CYP2D6 and CYP2C19.

2003

The Human Genome Project was successfully completed which helps us identify genes in the human body associated with both rare and common diseases and how our bodies process and metabolize foods and medications.

2004

The FDA approved the first PGx test—30 common variants in CYP2D6 and CYP2C19.

2009

CPIC (Clinical Pharmacogenetics Implementation Consortium) was established to provide expert guidance for healthcare providers using pharmacogenetic tests in patient care.

2010

The Food and Drug Administration (FDA) started including pharmacogenomic information in drug labels.

  1. Swen JJ, van der Wouden CH, Manson LE, et al; Ubiquitous Pharmacogenomics Consortium. A 12-gene pharmacogenetic panel to prevent adverse medication reactions: an open-label, multicentre, controlled, cluster-randomized crossover implementation study. Lancet. 2023;
  2. Auwerx C, Sadler MC, Reymond A, et al. From pharmacogenetics to pharmaco-omics: Milestones and future directions. HGG Ad
Brixner D, Biltaji E, Bress A, Unni S, Ye X, Mamiya T, et al. The effect of pharmacogenetic profiling with a clinical decision support tool on healthcare resource utilization and estimated costs in the elderly exposed to polypharmacy. J Med Econ. 2016;19:213–28.
  3. Zhang L, Jacobson PA, Johnson ANK, et al. Public Attitudes toward Pharmacogenomic Testing and Establishing a Statewide Pharmacogenomics Database in the State of Minnesota. J Pers Med. 2022 Sep 30;12(10):1615. doi: 10.3390/jpm12101615. 

In less than 5 minutes you can enroll in a 
free program that will provide medication 
insights throughout your lifetime.